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Additive Positive Stable Frailty Models
Authors:Madhuja Mallick  Nalini Ravishanker
Institution:(1) Merck Research Laboratories, RY34-A316, PO Box 2000, Rahway, NJ 07065, USA;(2) Department of Statistics, University of Connecticut, Storrs, CT 06269, USA
Abstract:In this article, we describe an additive stable frailty model for multivariate times to events data using a flexible baseline hazard, and assuming that the frailty component for each individual is described by additive functions of independent positive stable random variables with possibly different stability indices. Dependence properties of this frailty model are investigated. To carry out inference, the likelihood function is derived by replacing high-dimensional integration by Monte Carlo simulation. Markov chain Monte Carlo algorithms enable estimation and model checking in the Bayesian framework.
Keywords:Multivariate survival  Correlated prior process  Dependence
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