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Determination of plasma tranexamic acid using cation-exchange high-performance liquid chromatography with fluorescence detection |
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| Authors: | P M Elworthy S A Tsementzis D Westhead E R Hitchcock |
| Abstract: | A procedure is described for the determination of plasma tranexamic acid concentrations using cation exchange high-performance liquid chromatography with fluorescence detection following post-column derivatisation with omicron-phthalaldehyde. The chromatographic conditions were optimised with respect to detector performance and the method applied to measuring the plasma tranexamic acid levels of patients in a double-blind trial. |
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