Fibre-laser IR luminescence diagnostics of malignant tumours using rare earth porphyrins |
| |
| Authors: | M I Gaiduk V V Grigoryants A F Mironov V D Rumyantseva V I Chissov G M Sukhin |
| |
| Affiliation: | Institute of Radio Engineering and Electronics, U.S.S.R. Academy of Sciences, Moscow. |
| |
| Abstract: | To eliminate the masking effect of the background luminescence of endogenic substances in biological tissues and to increase the luminescence contrast values of malignant tumours, sarcoma-implanted mice were administered with ytterbium porphyrins instead of free porphyrin radicals. This was followed by in vivo luminescence localization of tumours using fibre-laser spectrofluorometry. The luminescence contrast values obtained reached 10-45 which is evidently not a limit. |
| |
| Keywords: | |
|
