Conductance titration of single-peptide molecules |
| |
Authors: | Xiao Xiaoyin Xu Bingqian Tao Nongjian |
| |
Institution: | Center for Solid State Electronics, Arizona State University, Tempe, Arizona 85287, USA. |
| |
Abstract: | We have measured the conductance of single peptides covalently bonded to two Au electrodes via S-Au bonds by repeatedly forming a large number of molecular junctions. The conductance decreases exponentially with the peptide length, with a decay constant of beta = 0.9 +/- 0.1 A-1, suggesting that tunneling is the mechanism of electron transport in the peptides. The conductance of the peptides is sensitive to the solution pH, due to the protonation/deprotonation of the amine and carboxyl groups of the peptides, which provides titration measurements based on single-molecule conductance. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|