Synthesis and antimicobacterial activity of 2-substituted 4-arylamino-6-methylpyrimidines |
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| Authors: | A V Erkin V I Krutikov E B Smirnova |
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| Institution: | (1) St. Petersburg State Technological Institute, Moskovskii pr. 26, St. Petersburg, 190013, Russia |
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| Abstract: | 2-Substituted 4-arylamino-6-methylpyrimidines were synthesized by stepwise modification of the structure of 6-methyl-2-thiouracyl through the intermediate 2-(ar)alkylthio-6-methyl-4-chloropyrimidines. Some of the compounds synthesized exhibit expressed antimycobacterial activity. |
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