Department of Chemistry, Faculty of Science and Technology, Keio University, Hiyoshi, Yokohama, Japan
Abstract:
Two new toxic substances, euphoscopins A and B, have been isolated from the plant L., and their absolute stereostructures also been elucidated on the basis of their spectral data coupled with an X-ray crystallographic analysis of the -bromobenzoate readily obtained on treatment of euphoscopin A with -bromobenzoyl chloride - pyridine. These antitumor substances belong to a group of jatrophone-type diterpenes.