| 反相高效液相色谱法测定苯醚甲环唑原药的含量 |
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| 引用本文： | 贺琼. 反相高效液相色谱法测定苯醚甲环唑原药的含量[J]. 广州化学, 2014, 39(4): 57-60 |
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| 作者姓名： | 贺琼 |
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| 作者单位： | 常州工程职业技术学院制药与生物工程技术系,江苏常州,213164 |
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| 摘 要： | 建立了反相高效液相色谱法测定苯醚甲环唑原药含量的方法,乙腈―水（体积比60∶40）为流动相,检测波长225 nm,流速1.0 m L/min,ODS C18色谱柱（250 mm×4.6 mm（i.d.）,2.5um）,紫外检测器。平均回收率为103.6%,标准偏差为0.37%,变异系数为0.38%;方法线性相关性系数0.999 7,适用于产品质量的检测分析。
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| 关 键 词： | 苯醚甲环唑 含量测定 反相高效液相色谱法 |
Determination of Difenoconazole in Original Drug by Reverse Phase High Performance Liquid Chromatography |
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| HE Qiong. Determination of Difenoconazole in Original Drug by Reverse Phase High Performance Liquid Chromatography[J]. Guangzhou Chemistry, 2014, 39(4): 57-60 |
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| Authors: | HE Qiong |
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| Affiliation: | HE Qiong ( Changzhou Institute of Engineering Technology, Changzhou 213164, China) |
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| Abstract: | A reverse phase high performance liquid chromatographic method was developed for the content of the difenoconazole original drug. Measurement conditions was by Column ODS（250 mm×4.6 mm（i.d.）, 2.5 um）, by UV detector with detection wavelength 225 nm in mobile phase of acetonitrile- water（V/V, 60∶40）, with flow rate of 1 m L/min. The results showed that the average recovery was 103.6% with standard deviation of 0.37% and variation coefficient of 0.38%, and the linear correlation coefficient was 0.999 7. The method was applicable to detection of the quality of the products. |
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| Keywords: | difenoconazole determination reverse phase high performance liquid chromatography |
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