a State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116012, China b State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China
Abstract:
Homogeneous Pd(OCOCF3)2/(R)-C4-TunePhos has been successfully applied in the asymmetric hydrogenation of simple ketones activated by catalytic amount of Brønsted acid with up to 88% ee.