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Palladium-catalyzed asymmetric hydrogenation of simple ketones activated by Brønsted acids
Authors:Xiao-Yu ZhouDuo-Sheng Wang  Ming Bao
Institution:a State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116012, China
b State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China
Abstract:Homogeneous Pd(OCOCF3)2/(R)-C4-TunePhos has been successfully applied in the asymmetric hydrogenation of simple ketones activated by catalytic amount of Brønsted acid with up to 88% ee.
Keywords:Palladium  Asymmetric hydrogenation  Brø  nsted acid  Simple ketones
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