2-Pyridones

The nitration of 6-phenyl-2-pyridone with 70% nitric acid, nitronium tetrafluoroborate, and acetyl nitrate has been studied for the first time. It was shown that, depending on the reaction temperature, the nitro group enters the 3 or 5 position of the heterocyclic ring. 3- Nitro-6-(p-nitrophenyl)-2-pyridone is formed by the action of fuming nitric acid on 6-phenyl-2-pyridone. The structures of the nitropyridones obtained were proved by PMR spectroscopy.See Zh. Organ. Khim., 7, 387 (1971) for communication V.Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1374–1378, October, 1972.