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Electrochemical current rectifier as a highly sensitive and selective cytosensor for cancer cell detection
Authors:Li Hailong  Li Dan  Liu Jiyang  Qin Yinan  Ren Jiangtao  Xu Shanling  Liu Yaqing  Mayer Dirk  Wang Erkang
Affiliation:State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China.
Abstract:Signal amplification originating from electrochemical current rectifier (ECR) was firstly applied to construct a cytosensor for rapid and non-invasive detection of folate receptor-rich cancer cells with high sensitivity. It exhibits a broad linear range with a detection limit as low as 10 cells mL(-1) even in the presence of a large number of normal cells.
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