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New tricyclic alkaloids, cassiarins G, H, J, and K from leaves of Cassia siamea
Authors:Deguchi Jun  Hirahara Tomoe  Hirasawa Yusuke  Ekasari Wiwied  Widyawaruyanti Aty  Shirota Osamu  Shiro Motoo  Morita Hiroshi
Institution:Faculty of Pharmaceutical Sciences, Hoshi University, 2–4–41 Ebara, Shinagawa, Tokyo, Japan.
Abstract:Four new alkaloids, cassiarins G, H, J, and K (1-4) which showed moderate antiplasmodial activity against Plasmodium falciparum 3D7, were isolated from the leaves of Cassia siamea (Leguminosae) and the structures of 1-4 were elucidated by 1D- and 2D-NMR analysis and X-ray crystallographic analysis.
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