New tricyclic alkaloids, cassiarins G, H, J, and K from leaves of Cassia siamea |
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Authors: | Deguchi Jun Hirahara Tomoe Hirasawa Yusuke Ekasari Wiwied Widyawaruyanti Aty Shirota Osamu Shiro Motoo Morita Hiroshi |
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Institution: | Faculty of Pharmaceutical Sciences, Hoshi University, 2–4–41 Ebara, Shinagawa, Tokyo, Japan. |
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Abstract: | Four new alkaloids, cassiarins G, H, J, and K (1-4) which showed moderate antiplasmodial activity against Plasmodium falciparum 3D7, were isolated from the leaves of Cassia siamea (Leguminosae) and the structures of 1-4 were elucidated by 1D- and 2D-NMR analysis and X-ray crystallographic analysis. |
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