Molecular Lamps and Molecular Golf Balls |
| |
Authors: | Ulrich Lüning Martin Hagen Frank Löffler Torsten Marquardt Bernd Meynhardt |
| |
Institution: | (1) Institut für Organische Chemie, Olshausenstr. 40, D-24098 Kiel, Germany |
| |
Abstract: | The concave shielding of the active site of enzymes has been transferred to standard reagents of organic chemistry and concave reagents have been synthesized which possess a lamp-like geometry (concave 1,10-phenanthrolines 1–2, concave pyridines 3). The special concave geometry of these reagents is responsible for their selectivity in metal ion catalyzed (Pd-catalyzed allylations, Cu(I)-catalyzed cyclopropanations) and base catalyzed (acylation of alcohols by ketenes) reactions. For an easier recovery, these reagents have been attached to Merrifield polymers and to dendrimers. Higher generations of dendrimers loaded with concave reagents will possess a golf ball geometry. |
| |
Keywords: | allylation calixarenes concave reagents cyclopropanation dendrimers metal ion catalysis |
本文献已被 SpringerLink 等数据库收录! |