A highly sensitive non-enzymatic glucose sensor based on a simple two-step electrodeposition of cupric oxide (CuO) nanoparticles onto multi-walled carbon nanotube arrays |
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Authors: | Jiang Yang Wei-De Zhang |
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Institution: | a Department of Biological Systems Engineering, University of Wisconsin-Madison, 460 Henry Mall, Madison, WI 53706, USA b Nanoscience Research Center, School of Chemistry & Chemical Engineering, South China University of Technology, Guangzhou 510630, People's Republic of China |
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Abstract: | A novel, stable and highly sensitive non-enzymatic glucose (Glc) sensor was developed using vertically well-aligned multi-walled carbon nanotubes array (MWCNTs) incorporated with cupric oxide (CuO) nanoparticles. The MWCNTs array was prepared by catalytic chemical vapor deposition on a tantalum (Ta) substrate, while a simple and rapid two-step electrodeposition technique was used to prepare the CuO-MWCNTs nanocomposite. First, Cu nanoparticles were deposited onto MWCNTs at constant potential and then they were oxidized into CuO by potential cycling. The electrocatalytic activity of CuO-MWCNTs array was investigated for Glc under alkaline conditions using cyclic voltammetry and chronoamperometry. The sensor exhibited a linear response up to 3 mM of Glc and sensitivity of 2190 μA mM−1 cm−2, which is two to three orders of magnitude higher than that of most non-enzymatic Glc sensors reported in the literature. The sensor response time is less than 2 s and detection limit is 800 nM (at signal/noise = 3). When tested with human blood serum samples, the sensor exhibited high electrocatalytic activity, stability, fast response and good selectivity against common interfering species, suggesting its potential to be developed as a non-enzymatic Glc sensor. |
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Keywords: | Carbon nanotube Cupric oxide Electrodeposition Glucose Non-enzymatic sensor |
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