Synthesis of 3-carbamoyl-1,2,4-oxadiazoles |
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| Authors: | Yarovenko V. N. Kosarev S. A. Zavarzin I. V. Krayushkin M. M. |
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| Affiliation: | (1) Russian Academy of Sciences, N. D. Zelinsky Institute of Organic Chemistry, 47 Leninsky prosp., 119991 Moscow, Russian Federation |
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| Abstract: | A convenient method for the synthesis of 3-carbamoyl-1,2,4-oxadiazoles from carbamoylamidoximes and chlorides or anhydrides of haloacetic acids was developed. The reactions of 3-carbamoyl-5-trichloromethyl-1,2,4-oxadiazoles with amines and N,N-dimethylhydrazine were studied. |
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| Keywords: | amidoximes 1,2,4-oxadiazoles acid chlorides trifluoroacetic anhydride |
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