Studies on the bacterial activity of cobalt(III) complexes. Part II. Cobalt(III) aminoacidato-complexes |
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Authors: | Ahmed Y. Ali-Mohamed Abdulla A. R. Abdulla |
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Affiliation: | (1) Department of Chemistry, University of Bahrain, College of Arts and Science, P.O. Box 1082, State of Bahrain |
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Abstract: | Summary Cobalt(III) complexes of the typetrans-[Co(AA)2(ox)] (where AA = aminoacidato, gly = glycinato, sar = sarcosinato, DL-ala = DL-alaninato, L-ala = L-alaninato; ox = oxalate); [Co(L-val)2CO3] and DL-[Co(en)2sar]I2 where L-val = L-valinato, en = ethylenediamine) have been investigated for their bacterial activity againstEscherichia coli B using well-cultured techniques on EMB agar and in minimal glucose media. The activities decrease in the order:trans-(N)(+)K[Co(sar)2(ox)] >trans-(N)(+)K[Co(L-ala)2(ox)] >trans-(N)(–)K[Co (gly)2(ox)] >trans-(N)(+)K[Co(DL-ala)2(ox)] >trans-(N)(+)K[Co(gly)2(ox)] >trans(+)K[Co(DL-ala)2(ox)] >trans-K[Co(L-val)2CO3]. |
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