Diastereoselective synthesis of cyclopentanediols by InCl 3/Al mediated intramolecular pinacol coupling reaction in aqueous media |
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| Authors: | Chen Yunhua Wan Jieping Wang Chunyan Sun Cuirong |
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| Affiliation: | Zhejiang Hisun Pharm. Co. Ltd. Taizhou, PR China. |
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| Abstract: | A "green" and practical intramolecular pinacol coupling reaction promoted by InCl 3/Al catalysts in aqueous media has been developed. Under mild conditions, a novel class of polysubstituted cyclopentane-1,2-diols have been obtained with excellent diastereoselectivity. |
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