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A new compound with cytotoxic activities from the leaves of Panax ginseng C.A. Meyer
作者姓名:Li Bo Wang  Zhao Hua Wu  Hui Yuan Gao  Jian Huang  Bo Hang Sun  Li Jun Wu
作者单位:a School of Traditional Chinese Materia. Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;b Department of Pharmacology, Mudanjiang Medical College, Mudanjiang 157001, China
摘    要:A new compound, 3,6,20(S)-trihydroxy- 12,23-epoxydammar-24-ene,6,20-di-O-β-D-glucopyranoside (1), was isolated from the leaves of Panax ginseng C.A. Meyer, whose structural elucidation was carried out by means of spectral analysis (including IR, HR- FAB-MS and NMR). This compound showed the moderate cytotoxic activities against U937 and HeLa cells by using the MTT method.

关 键 词:人参  细胞毒素  植物生物化学  化合物

A new compound with cytotoxic activities from the leaves of Panax ginseng C.A. Meyer
Li Bo Wang,Zhao Hua Wu,Hui Yuan Gao,Jian Huang,Bo Hang Sun,Li Jun Wu.A new compound with cytotoxic activities from the leaves of Panax ginseng C.A. Meyer[J].Chinese Chemical Letters,2008,19(7):837-840.
Authors:Li Bo Wang  Zhao Hua Wu  Hui Yuan Gao  Jian Huang  Bo Hang Sun  Li Jun Wu
Institution:a School of Traditional Chinese Materia. Medica, Shenyang Pharmaceutical University, Shenyang 110016, China;b Department of Pharmacology, Mudanjiang Medical College, Mudanjiang 157001, China
Abstract:A new compound,3,6,20(S)-trihydroxy-12,23-epoxydammar-24-ene,6,20-di-O-β-D-glucopyranoside (1),was isolated from the leaves of Panax ginseng C.A.Meyer,whose structural elucidation was carried out by means of spectral analysis (including IR,HRFAB-MS and NMR).This compound showed the moderate eytotoxie activities against U937 and HeLa ceils by using the MTT method.
Keywords:Panax ginseng  Cytotoxic activity
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