Efficient synthesis of alpha-galactosyl ceramide analogues using glycosyl iodide donors |
| |
Authors: | Du Wenjun Gervay-Hague Jacquelyn |
| |
Affiliation: | University of California, Davis, Department of Chemistry, 95616, USA. |
| |
Abstract: | The combination of reactive galactosyl iodide donors with electron-rich acceptor lipids provides highly stereoselective and efficient routes to alpha GalCer analogues. Using per-O-silylated donors, key intermediates can be obtained in a three-step, one-pot sequence providing useful constructs for analogue development. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|