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Formal catalytic asymmetric total synthesis of fostriecin |
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| Authors: | Fujii Kunihiko Maki Keisuke Kanai Motomu Shibasaki Masakatsu |
| Affiliation: | Graduate School of Pharmaceutical Sciences, The University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. |
| Abstract: | The common synthetic intermediate of a potent and promising anticancer agent, fostriecin, was synthesized using a unique method that combines four catalytic asymmetric reactions as shown above. |
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