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Recent developments in analytical applications of quantum dots
Authors:Hua Kuang  Yuan Zhao  Wei MaLiguang Xu  Libing Wang  Chuanlai Xu
Affiliation:a School of Food Science and Technology, State Key Lab of Food Science and Technology, Jiangnan University, Wuxi, JiangSu 214122, PR China
b Hunan Entry-Exit Inspection and Quarantine Bureau, Changsha 410001, PR China
Abstract:This review discusses the application of quantum dots (QDs) to chemical and biological detection, for which they have excellent features, particularly size-dependent optical properties.We can summarize the main areas discussed in this review as follows:(1) QDs associated with enzyme-linked immunosorbent assay (ELISA), chip detection and capillary electrophoresis (CE) enhance the sensitivity and the speed of detection of residues;(2) QDs are applied with other techniques, including polymerase chain reaction (PCR), fluorescence resonance-energy transfer (FRET) analysis, fluorescence in-situ hybridization (FISH) and western blot analysis; and,(3) QDs combined with the above techniques can successfully detect DNA and protein.We also cover perspectives and challenges in analytical applications of QDs.
Keywords:Biological detection   Capillary electrophoresis   Chemical detection   Enzyme-linked immunosorbent assay   Fluorescence in-situ hybridization   Fluorescence resonance-energy transfer   Immunoassay   Polymerase chain reaction   Quantum dot   Western blot
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