Recent developments in analytical applications of quantum dots |
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Authors: | Hua Kuang Yuan Zhao Wei MaLiguang Xu Libing Wang Chuanlai Xu |
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Affiliation: | a School of Food Science and Technology, State Key Lab of Food Science and Technology, Jiangnan University, Wuxi, JiangSu 214122, PR China b Hunan Entry-Exit Inspection and Quarantine Bureau, Changsha 410001, PR China |
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Abstract: | This review discusses the application of quantum dots (QDs) to chemical and biological detection, for which they have excellent features, particularly size-dependent optical properties.We can summarize the main areas discussed in this review as follows:(1) QDs associated with enzyme-linked immunosorbent assay (ELISA), chip detection and capillary electrophoresis (CE) enhance the sensitivity and the speed of detection of residues;(2) QDs are applied with other techniques, including polymerase chain reaction (PCR), fluorescence resonance-energy transfer (FRET) analysis, fluorescence in-situ hybridization (FISH) and western blot analysis; and,(3) QDs combined with the above techniques can successfully detect DNA and protein.We also cover perspectives and challenges in analytical applications of QDs. |
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Keywords: | Biological detection Capillary electrophoresis Chemical detection Enzyme-linked immunosorbent assay Fluorescence in-situ hybridization Fluorescence resonance-energy transfer Immunoassay Polymerase chain reaction Quantum dot Western blot |
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