A novel antimicrobial triterpenic acid from the leaves of Ficus benjamina (var. comosa) |
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| Authors: | Mehtab Parveen Raza Murad Ghalib Sayed Hasan Mehdi Rayees Ul Hasan Mattu Mohammed Ali |
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| Institution: | 1. Department of Chemistry, Aligarh Muslim University, Aligarh 202002, UP, India;2. Department of Biochemistry, Aligarh Muslim University, Aligarh 202002, UP, India;3. Faculty of Pharmacy, Jamia Hamdard, New Delhi 110062, India |
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| Abstract: | The chloroform extract of the leaves of Ficus benjamina (var. comosa) (Moraceae) afforded a new triterpenic acid named as (9,11), (18,19)-disecoolean-12-en-28-oic acid (1) along with β-amyrin (2). Their structures were established on the basis of chemical and physical evidences (IR, 1H NMR, and MS data). The compound 1 exhibited significant antimicrobial activity against Salmonella typhimurium (MTCC-98), Candida albicans (IAO-109), Staphylococcus aureus (IAO-SA-22), Escherichia coli (K-12) and low activity against Aspergillus niger (lab isolate ICAR) and Aspergillus brassicola. |
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| Keywords: | Moraceae Triterpenoids β-Amyrin (9 11) (18 19)-Disecoolean-12-en-28-oic acid |
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