Enantioselective aldol reaction of trimethoxysilyl enol ether catalyzed by lithium binaphtholate |
| |
Authors: | Nakajima Makoto Orito Yuya Ishizuka Tadao Hashimoto Shunichi |
| |
Affiliation: | Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, 5-1 Oe-honmachi, Kumamoto 862-0973, Japan. nakajima@gpo.kumamoto-u.ac.jp |
| |
Abstract: | [reaction: see text] An aldol reaction of trimethoxysilyl enol ether catalyzed by lithium binaphtholate, in which water serves as an additive and plays a pivotal role in stereoselectivities, was developed. This is the first example of an aldol reaction of trimethoxysilyl enol ether catalyzed by a chiral base. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|