New (S)-proline derivatives as catalysts for the enantioselective aldol reaction |
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Authors: | V. I. Maleev Z. T. Gugkaeva M. A. Moskalenko A. T. Tsaloev K. A. Lyssenko |
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Affiliation: | 1.A. N. Nesmeyanov Institute of Organoelement Compounds,Russian Academy of Sciences,Moscow,Russian Federation |
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Abstract: | (2S)-N- 2-[(R)-Hydroxy(phenyl)methyl]phenylpyrrolidine-2-carboxamide, (2 S)-N-{2-[(S)-hydroxy(phenyl)methyl]phenyl}pyrrolidine-2-carboxamide, and (S)-N-{2-[hydroxy-(diphenyl)methyl]phenyl}pyrrolidine-2-carboxamide were obtained and tested as catalysts for an asymmetric aldol reaction of 4-nitrobenzaldehyde with acetone. |
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