Bi-directional interhemispheric inhibition during unimanual sustained contractions |
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Authors: | Aimee J Nelson Tasnuva Hoque Carolyn Gunraj Zhen Ni and Robert Chen |
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Institution: | (1) Division of Neurology and Krembil Neuroscience Centre, Toronto Western Research Institute, University of Toronto, Toronto, Canada;(2) Department of Kinesiology, University of Waterloo, Waterloo, Canada |
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Abstract: | Background The interaction between homologous muscle representations in the right and left primary motor cortex was studied using a paired-pulse
transcranial magnetic stimulation (TMS) protocol known to evoke interhemispheric inhibition (IHI). The timecourse and magnitude
of IHI was studied in fifteen healthy right-handed adults at several interstimulus intervals between the conditioning stimulus
and test stimulus (6, 8, 10, 12, 30, 40, 50 ms). IHI was studied in the motor dominant to non-dominant direction and vice
versa while the right or left hand was at rest, performing isometric contraction of the first dorsal interosseous (FDI) muscle,
and isometric contraction of the FDI muscle in the context of holding a pen. |
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Keywords: | |
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