Synthesis of C3-dihydrofuran substituted coumarins via multicomponent approach |
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| Authors: | Venkata Swamy Tangeti Ramesh Varma K G V Siva Prasad K V V V Satyanarayana |
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| Institution: | 1. Raghu Engineering College, Visakhapatnam, Andhra Pradesh, Indiaswamychempcu8@gmail.com;3. Sri Venkateswara University, Tirupathi, India;4. Raghu Engineering College, Visakhapatnam, Andhra Pradesh, India |
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| Abstract: | An efficient method was developed for the synthesis of dihydrofuran substituted coumarin from a one-pot, four-component reaction of 2-hydroxy aromatic aldehydes, 6-methyl, 4-hydroxy pyranone, aromatic aldehyde, and pyridinium ylide in the presence of tri-ethylamine under microwave irradiation. The reaction proceeds under solvent-free conditions to afford C3-dihydrofuran substituted coumarin in a diastereoselective manner in good yields (71–89%). |
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| Keywords: | C3-dihydrofuran substituted coumarin microwave-assisted synthesis multicomponent pyridinium ylide |
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