Efficient three-step synthesis of benzo[e]imidazo[1,2-c][1,2,3]triazines |
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| Authors: | Hedieh Pilali Shirin Faraji Kamazani Shahram Moradi Setareh Moghimi Mohammad Mahdavi Loghman Firoozpour |
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| Institution: | 1. Department of Chemistry, North Tehran Branch, Islamic Azad University, Tehran, Iran;2. Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran;3. Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran |
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| Abstract: | A novel three-step sequence toward benzoe]imidazo1,2-c]1,2,3]triazine derivatives is investigated. This pathway started from commercially available starting materials afforded 5a–h in good to excellent yields. In this method, we took the advantage of diazonium chemistry, which was followed by intramolecular N-N bond formation in the construction of N-rich cycles. |
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| Keywords: | Benzotriazine diazonim salt heterocyclization imidazole N-N bond |
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