Microwave-assisted catalyst-free synthesis of tetrasubstituted pyrroles using dialkyl acetylenedicarboxylates and monophenacylanilines |
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| Authors: | Arumugam Mariappan Kandasamy Rajaguru Nattamai Bhuvanesh |
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| Affiliation: | 1. Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai, India;2. X-ray Diffraction Laboratory, Department of Chemistry, Texas A &3. M University, College Station, Texas, USA |
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| Abstract: | An efficient catalyst-free microwave-assisted synthesis of tetrasubstituted pyrroles using dialkyl acetylenedicarboxylates and substituted monophenacylanilines has been developed. Axial chirality has been noticed in some N-(α-naphthyl/2-isopropylphenyl)-2,3-dicarbethoxy-4-arylpyrroles, but not with N-aryl-2,3-dicarbethoxy-4-(α-naphthyl)pyrrole. |
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| Keywords: | Axial chirality diethylacetylene dicarboxylate microwave synthesis polysubstituted pyrrole |
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