A sulfated glycoside from the preparation “tribestan”

The chemical composition and structures of the steroid glycosides forming the active principle of the preparation “tribestan,” which is used for treating impotence and female infertility, have been studied. It has been shown that together with trillin, prosapogenin A of dioscin, trillarin, dioscin, gracillin, protodioscin, and protogracillin, tribestan contains a diosgenin rhamnoglucoside sulfated in position 4 of the glucose residue, the structure of which has been shown by chemical and physicochemical methods. Institute of Ecological Genetics, Academy of Sciences of the Moldavian SSR, Kishinev. Center for Biogenic Stimulators, Sofia, Bulgaria. N. D. Zelinskii Institute of Organic Chemistry, Academy of Sciences of the USSR, Moscow. Translated from Khimiya Prirodnykh Soedinenii, No. 5, pp. 649–652, September–October, 1990.