Abstract: | Various N′,N-bis(8-quinolyl) trimethylenediamines 3a-3e have been prepared from the corresponding 8-aminoquinolines 1a-1e by direct N-alkylation with 1, 3-dibromopropane in fair yield (25-51%). N. N′-bis(8-quinolyl) ethylenediamines, 3f and 3g, and N,N′-bis(8-(6-methoxyquinolyl) ]tetramethylenediamine. 3h, may only be synthesized in poor yield via the corresponding oxalamides and succinamide. |