Synthèse partielle et propriétés oncostatiques des pseudo-tubulosines,analogues de l'émétine et de la tubulosine |
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Authors: | Elisabeth Seguin Michel Koch Evelyne Chenu Marcel Hayat |
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Abstract: | Partial Synthesis and Oncostatic Properties of Pseudotubulosines, Analogues of Emetine and Tubulosine Pseudotubulosines, structural analogues of emetine and tubulosine, have been synthesized by either Pictet-Spengler or Bischler-Napieralski condensation from dihydrocorynantheal or corynantheidal. Spectral data, cytotoxic and oncostatic properties of these new alkaloids are described. |
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