A synthesis of some novel 4,5-dihydroazepines by the reaction of oxazolium 5-oxides with 1,2-dicyanocyclobutene |
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Authors: | Ignatius J. Turchi Cynthia A. Maryanoff Antonietta R. Mastrocola |
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Abstract: | Heating primary or secondary α-amino acids in acetic anhydride in the presence of 1,2-dicyanocyclobutene leads to 4,5-dihydroazepines via the intermediacy of mesoionic oxazolium 5-oxides. |
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