Synthesis of polymer containing lipoic acid as a polymeric reagent for acyl transfer

Lipoic acid was immobilized on crosslinked polystyrene beads to generate a polymeric reagent. The acyl transfer reaction of the p-nitrobenzoyl group from the polymer-bound lipoic acid to cyclohexylamine was investigated spectrophotometrically and was compared with a monomeric model compound. The acceleration effect of silver ion on the acyl transfer reaction also was studied.