Lipophilic Di- and Triamides as Ionophores for Alkaline Earth Metal Cations |
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| Authors: | Daniel Erne Nada Stojanac Daniel Ammann Peter Hofstetter Ern Pretsch Wilhelm Simon |
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| Institution: | Daniel Erne,Nada Stojanac,Daniel Ammann,Peter Hofstetter,Ernö Pretsch,Wilhelm Simon |
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| Abstract: | Different electrically neutral lipophilic di- and triamides were prepared and their ion selectivity in membranes studied. In membranes the ionophore N, N′-diheptyl-N, N′-dimethyl-succinamide prefers Ca2+ over Mg2+ by a factor of 20 but rejects Na+ and K+ in respect to Mg2+ by a factor of 100 and 10, respectively. This selectivity suffices to perform useful intracellular Mg2+ activity studies. |
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