Synthesis of pyrimido [4,5-c] pyridazine (4-deazafervenulin), pyrazolo[3,4-d] pyrimidine and 6-(pyrazino-1-yl)pyrimidine derivatives |
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Authors: | Vishnu J Ram Hrishi Kesh Pandey Arnold J Vlietinck |
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Abstract: | The synthesis of several pyrimido4,5-c]pyridazine (4-deazafervenulin) ( 1 ), pyrazolo3,4-d]-pyrimidine ( 2 ) and 6-(pyrazino-1-yl)pyrimidine ( 9 ) analogs has been accomplished from 6-hydrazinouracil ( 3 ). This compound could not be used as starting material for the preparation of indolo3,2-c]pyridazino3,4-d]pyrimidine derivatives ( 8 ) because it yielded the corresponding hydrazones ( 7 ). |
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