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Speradine A, a new pentacyclic oxindole alkaloid from a marine-derived fungus Aspergillus tamarii |
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| Authors: | Masashi TsudaTakao Mugishima Kazusei KomatsuTeruo Sone Michiko TanakaYuzuru Mikami Motoo ShiroManabu Hirai Yasushi OhizumiJun'ichi Kobayashi |
| Affiliation: | a Graduate School of Pharmaceutical Sciences, Hokkaido University, Kita-12 Nishi-6, Kita-ku, Sapporo 0600812, Japan b Graduate School of Agriculture, Hokkaido University, Sapporo 060-8589, Japan c Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, Chiba 260-0856, Japan d X-Ray Research Laboratory, Rigaku Corporation, Akishima, Tokyo 196-8666, Japan e Graduate School of Pharmaceutical Sciences, Tohoku University, Sendai 980-0845, Japan |
| Abstract: | A new pentacyclic oxindole alkaloid, speradine A (1), was isolated from the cultured broth of a fungus Aspergillus tamarii, which was separated from driftwood at a seashore in Okinawa. The structure and relative stereochemistry were determined by spectroscopic data and a single crystal X-ray diffraction analysis. |
| Keywords: | speradine A oxindole alkaloid Aspergillus tamarii |
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