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An improved synthesis of rhinocerotinoic acid |
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| Authors: | Christopher A GrayMichael T Davies-Coleman Douglas EA Rivett |
| Institution: | Department of Chemistry, Rhodes University, Grahamstown 6140, South Africa |
| Abstract: | The stereoselective synthesis of E-rhinocerotinoic acid has been achieved in five steps from (−)-sclareol in an overall yield of 32%. This constitutes a significant improvement on the previous synthesis of this anti-inflammatory compound. |
| Keywords: | labdane diterpene rhinocerotinoic acid synthesis |
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