The reaction of (N‐isocyanimino) triphenylphosphorane with an electron‐poor α‐haloketone in the presence of aromatic carboxylic acids: A novel three‐component reaction for the synthesis of disubstituted 1,3,4‐oxadiazole derivatives |
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| Authors: | Ali Ramazani Yavar Ahmadi Morteza Rouhani Nahid Shajari Ali Souldozi |
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| Abstract: | Reactions of electron‐poor α‐haloketones with (N‐isocyanimino) triphenylphosphorane in the presence of aromatic carboxylic acids proceed smoothly at room temperature and in neutral conditions to afford disubstituted 1,3,4‐oxadiazole derivatives in high yields. © 2010 Wiley Periodicals, Inc. Heteroatom Chem 21:368–372, 2010; View this article online at wileyonlinelibrary.com . DOI 10.1002/hc.20626 |
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