Synthesis of N-substituted 7-aryl-5-methyl-4,7-dihydrotetrazolo[1,5-<Emphasis Type="Italic">a</Emphasis>]pyrimidine-6-carboxamides |
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| Authors: | V L Gein T M Zamaraeva N V Nosova M I Vakhrin P A Slepukhin |
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| Institution: | 1.Perm State Pharmaceutical Academy,Perm,Russia;2.Postovskii Institute of Organic Synthesis, Ural Division,Russian Academy of Sciences,Yekaterinburg,Russia |
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| Abstract: | Three-component reaction of N-methyl- or N,N-diethyl-3-oxobutanamide with aromatic aldehydes and tetrazol-5-amine monohydrate gave the corresponding N-substituted 7-aryl-5-methyl-4,7-dihydrotetrazolo-1,5-a]pyrimidine-6-carboxamides. |
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