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几类甲基丙烯酸pH—敏感水凝胶的溶胀行为研究
引用本文:徐国刚 窦东友. 几类甲基丙烯酸pH—敏感水凝胶的溶胀行为研究[J]. 离子交换与吸附, 1999, 15(6): 487-495
作者姓名:徐国刚 窦东友
作者单位:华东师范大学化学系!上海,200062
摘    要:本文合成了以甲基丙烯酸为基础的各类pH敏感型水凝胶,并研究它们的溶胀行为。初步探索了水凝胶的组成与其pH敏感的关系,比较了阴离子型水凝胶、阳离子型水凝胶和两性水凝胶的溶胀热力学动力学行为,得出了两性水凝胶在整个pH范围内都有一定的溶胀比,且在pH中性时,其溶胀速率要高于相应的阴离子型和阳离子型水凝胶。

关 键 词:水凝胶 pH敏感 甲基丙烯酸 溶胀比曲线 药物控释

STUDIES ON THE SWELLING BEHAVIORS OF SEVERAL KINDS OF ACRYLIC-ACID pH-SENSITIVE HYDROGELS
XU Guogang, DOU Dongyou, XU Rongnan, YAN Jun. STUDIES ON THE SWELLING BEHAVIORS OF SEVERAL KINDS OF ACRYLIC-ACID pH-SENSITIVE HYDROGELS[J]. Ion Exchange and Adsorption, 1999, 15(6): 487-495
Authors:XU Guogang   DOU Dongyou   XU Rongnan   YAN Jun
Abstract:Several kinds of pH-sensitive hydrogels based on acrylic acid were synthesized andstudies on their swelling behaviors were also undertaken. Influence of composition of hydrogelson their swelling behaviors was studied. Comparisons on swelling behaviors of cationic, anionicand amphoteric hydrogels were made. Compared with the cationic and anionic hydrogels,amphoteric hydrogels had a certain degree of swelling (DS) at the whole range of pH and a morerapid swelling speed than its counterparts at pH=7.00.
Keywords:Hydrogels   pH-sensitivity  Acrylic acid   Swelling ratio curve
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