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Gibberellic acid production by free and immobilized cells in different culture systems
Authors:Enrique Durán-Páramo  Héctor Molina-Jiménez  Marco A Brito-Arias  Fabián Robles-Martínez
Institution:(1) Bioprocess Department, Unit of Biotechnology (UPIBI), National Polytechnic Institute, Ave. Acueducto s/n La Laguna, 07340 Ticomán, Mexico, D.F.
Abstract:Gibberellic acid production was studied in different fermentation systems. Free and immobilized cells of Gibberella fujikuroi cultures in shakeflask, stirred and fixed-bed reactors were evaluated for the production of gibberellic acid (GA3). Gibberellic acid production with free cells cultured in a stirred reactor reached 0.206 g/L and a yield of 0.078 g of GA3/g biomass.
Keywords:Cell immobilization  gibberellic acid            Gibberella fujikuroi            shake flasks  free cells  immobilized cells
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