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Simple total synthesis of 18-hydroxyestrone
Authors:Jiro Tsuji  Hiroshi Okumoto  Yuichi Kobayashi  Takashi Takahashi
Institution:Tokyo Institute of Technology, Meguro, Tokyo 152, Japan
Abstract:A simple total synthesis of 18-hydroxyestrone (7) was carried out by the cycloaddition of o-quinodimethane intermediate. 2-Methoxycarbonyl-3-vinyl-cyclopentanone (1) was used as the D ring component.
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