Simple total synthesis of 18-hydroxyestrone |
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Authors: | Jiro Tsuji Hiroshi Okumoto Yuichi Kobayashi Takashi Takahashi |
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Institution: | Tokyo Institute of Technology, Meguro, Tokyo 152, Japan |
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Abstract: | A simple total synthesis of 18-hydroxyestrone () was carried out by the cycloaddition of o-quinodimethane intermediate. 2-Methoxycarbonyl-3-vinyl-cyclopentanone () was used as the D ring component. |
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