Synthese von oligosaccharid-determinanten des T-antigens mit amid-spacer zur darstellung synthetischer antigene

The β (1 → 3) -linked disaccharide $\text{1}$$\text{5}$ was synthesized from $\text{D}$-galactose and a $\text{D}$-galactosamine unit with a watersoluble amide spacer. This represents the hapten of T-antigen and, when coupled to a protein, is suitable for use as an artificial antigen. Other O-β-$\text{D}$-galactosylated derivatives of galactosamine were synthesized.