Synthesis and Crystal Structure of (<Emphasis Type="Italic">S</Emphasis>)-2-((<Emphasis Type="Italic">S</Emphasis>)-2-(<Emphasis Type="Italic">N</Emphasis>-Ts-Amino)-3-methylbutanoyl)-3-(1H-indol-3-yl)-6-phenyl-3,4-dihydro-1,2,4-triazin-5(2H)-one |
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| Authors: | Ilya N Egorov Vladimir L Rusinov Pavel A Slepukhin Oleg N Chupakhin |
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| Institution: | (1) Department of Organic Chemistry, Urals State Technical University, 19, Ul. Mira, Ekaterinburg, 620002, Russian Federation;(2) Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 20, Ul. S. Kovalevskaya, Ekaterinburg, 620219, Russian Federation |
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| Abstract: | Abstract The diastereoselective synthesis, NMR and X-ray structure of (S)-2-((S)-2-(N-Ts-amino)-3-methylbutanoyl)-3-(1H-indol-3-yl)-6-phenyl-3,4-dihydro-1,2,4-triazin-5(2H)-one—a potential antivirus agent are
reported. The compound crystallizes in the triclinic space group P1 with unit cell parameters: a = 5.9259(6) ?, b = 9.6370(12) ?, c = 12.9541(9) ?, α = 109.210(9)°, β = 90.804(7)°, γ = 105.074(10)° and Z = 1. |
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