The cyclodextrin-nicotinamide compound as a dehydrogenase model simulating apoenzyme-coenzyme-substrate ternary complex system |
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| Authors: | Masayoshi Kojima Fujio Toda Kenjiro Hattori |
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| Affiliation: | Department of Synthetic Chemistry, Faculty of Engineering, the University of Tokyo, Hongo, Bunkyo-ku, Tokyo 113 Japan;Department of Industrial Chemistry, Faculty of Engineering, Tokyo Institute of Polytechnics, Atsugi, Kanagawa 243-02 Japan |
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| Abstract: | The cyclodextrin-dihydronicotinamde had a dihydronicotinamde group at the open side of cyclodextrin cavity, and showed a large rate enhancement in the reduction of substrate upon complexation comparing with NADH. |
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