Direct synthesis of the antitumor agent -α-amino-3-bromo-4,5-dihydroisoxazole-5-acetic acid |
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Authors: | Alfred A. Hagedorn Bryan J. Miller Jon O. Nagy |
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Affiliation: | Department of Chemistry Rutgers-The State University of New Jersey New Brunswick, New Jersey 08903 U.S.A. |
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Abstract: | Generation of bromonitrile oxide in the presence of vinylglycine leads to the formation of the title compound and its isomer in good yield. |
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