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Direct synthesis of the antitumor agent erythro-α-amino-3-bromo-4,5-dihydroisoxazole-5-acetic acid
Authors:Alfred A. Hagedorn  Bryan J. Miller  Jon O. Nagy
Affiliation:Department of Chemistry Rutgers-The State University of New Jersey New Brunswick, New Jersey 08903 U.S.A.
Abstract:Generation of bromonitrile oxide in the presence of vinylglycine leads to the formation of the title compound 2 and its threo isomer in good yield.
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