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A simple synthesis of 2,2-disubstituted tetrahydrothiophenes |
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| Authors: | Gholam Hosein Hakimelahi George Just |
| Affiliation: | Department of Chemistry, McGill University, Montreal, Canada H3A 2K6. |
| Abstract: | Treatment of diethyl 2-(3-mesyloxypropyl) malonate with KSCOCH3/DMF at room temperature gave 2,2-dicarbethoxytetrahydrothiophene. The reaction can be used to prepare isopenams in good yield.  |
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