6-amino-1H-pyrrolo[3,2-c]pyridin-4(5H)-one (3,7-dideazaguanine) |
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| Authors: | Stewart W Schneller Jiann-Kuan Luo Ramachandra S Hosmane |
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| Institution: | Department of Chemistry, University of South Florida, Tampa, Florida 33620 USA |
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| Abstract: | The synthesis of 6-amino-1H-pyrrolo3,2-c]pyridin-4(5H)-one (3,7-dideazaguanine) from the ammonium chloride promoted reaction of 3-(ethoxycarbonyl)pyrrole-2-acetonitrile and ammonia is reported. Several preliminary reactions which led to this synthetic route are also described. |
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