Facile synthesis of Gramicidin S via cyclication of a linear pentapeptide |
| |
| Authors: | Yoshihiro Minematsu Michinori Waki Kazushi Suwa Tetsuo Kato Nobuo Izumiya |
| |
| Institution: | Laboratory of Biochemistry, Faculty of Science, Kyushu University 33, Higashi-ku, Fukuoka 812, Japan |
| |
| Abstract: | Azide and N-hydroxysuccinimide ester of five pentapeptides related to gramicidin S (cyclic decapeptide) were cyclized to determine the ratio of dimer to monomer in the cyclization product, the pentapeptide derivative with D-Phe as C-terminus giving the dimer in good yield. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
