New improvements in oligonucleotide synthesis by use of the p-nitrophenylethyl phosphate blocking group and its deprotection by DBU or DBN |
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| Authors: | Eugen Uhlmann Wolfgang Pfleiderer |
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| Affiliation: | Fakultät für Chemie, Universität Konstanz, Postfach 5560, D-7750 Konstanz/West Germany |
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| Abstract: | Phosphate protection in the phosphotriester approach is improved by the new, versatile p-nitrophenylethyl group due to its stability in the condensation step and its clean removal by DBU and DBN respectively. |
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